An Automated Storage and Retrieval System (AS/RS) operates a shuttle with computer process control to execute the storage and retrieval of warehouse stock. It can be equipped with the traditional single shuttle or the newly developed twin shuttle. There has been a significant literature on the comparison of single shuttle systems versus twin shuttle systems. Researchers agree that twin shuttle ...

Increasing evidence suggests that glutamate activates the generation of lactate from glucose in astrocytes; this lactate is shuttled to neurons that use it as a preferential energy source. We explore this multicellular "lactate shuttle" with a novel dual-cell, dual-gene therapy approach and determine the neuroprotective potential of enhancing this shuttle. Viral vector-driven overexpression of ...

An integrated optimization framework, including location assignment under grouping class-based storage policy and schedule of dual shuttle cranes, is offered by presenting a new optimization programming model. The objective functions, which are considered at this level, are the minimization of total costs and energy consumption. Scheduling of dual shuttle cranes among specified locations, which...

We read with interest Luzardo et al’s technical note in the December issue of the AJNR. Although we are pleased that the new Envoy 6F guide catheter (Cordis, Miami Lakes, Fla) facilitated a dualmicrocatheter procedure with a single arterial access, it should be noted that this is by no means a new technique. The 6F Envoy guide catheter with an inner diameter of 0.070 inches and outer diameter o...

This paper presents an asynchronous high-performance FPGA that combines Four-Phase Dual-Rail (FPDR) protocol and Level-Encoded Dual-Rail (LEDR) protocol. FPDR protocol is employed to achieve small area for logic blocks, while LEDR protocol is employed to obtain high bit rate and low power for data transfer. Each logic block consists of LEDRFPDR protocol converter, FPDR-LEDR protocol converter a...

[1] The Shuttle Radar Topography Mission produced the most complete, highest-resolution digital elevation model of the Earth. The project was a joint endeavor of NASA, the National Geospatial-Intelligence Agency, and the German and Italian Space Agencies and flew in February 2000. It used dual radar antennas to acquire interferometric radar data, processed to digital topographic data at 1 arc s...

Ddi1 belongs to a family of shuttle proteins targeting polyubiquitinated substrates for proteasomal degradation. Unlike the other proteasomal shuttles, Rad23 and Dsk2, Ddi1 remains an enigma: its function is not fully understood and structural properties are poorly characterized. We determined the structure and binding properties of the ubiquitin-like (UBL) and ubiquitin-associated (UBA) domain...